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The Late Show with Stephen Colbert
Season 10 · Episode 140
Owen Wilson, Dr. Francis Collins
4.041mJuly 16, 2025
Missing 2:53. Late Show Presents: Meanwhile. Owen Wilson takes "The Colbert Questionert". Dr. Francis Collins discusses recent politics and his new book, 'The Road to Wisdom'.
Episodes
- Episode 1Supreme Court Justice Ketanji Brown Jackson
- Episode 2Curtis "50 Cent" Jackson, Jack Lowden
- Episode 3Stephen Curry, Senator Mark Kelly
- Episode 4Jim Parsons, Natasha Rothwell
- Episode 5John Dickerson, Tems
- Episode 6Samuel L. Jackson, Amy Ryan
- Episode 7Jeff Bridges
- Episode 8Jeremy Strong, Dr. Francis Collins
- Episode 9Rachel Maddow, Shaboozey
- Episode 10Anderson Cooper, Sting
- Episode 11Justin Trudeau, RuPaul Charles
- Episode 12Kate Winslet, Jude Law
- Episode 13Bill Gates, Jane Goodall
- Episode 14Sarah Silverman, Chris Stapleton
- Episode 15Don Cheadle, Malcolm Gladwell
- Episode 16Chris Hayes, Brittany Howard
- Episode 17Andrew Garfield, Ina Garten
- Episode 18Chris Wallace, Yotam Ottolenghi
- Episode 19Vice President Kamala Harris
- Episode 20Kathy Bates, Pamela Anderson
- Episode 21Jason Segel, Representative Jasmine Crockett
- Episode 22Stanley Tucci, Harvey Guillén
- Episode 23Bob Woodward, Wyatt Flores
- Episode 24Brian Cox, Yulia Navalnaya
- Episode 25Senator John Fetterman, Alfonso Cuarón
- Episode 26Anna Kendrick, Matty Matheson
- Episode 27Julia Louis-Dreyfus, Jonathan Alter, Jhayco
- Episode 28Robin Wright, Nicole Scherzinger
- Episode 29Tom Hanks, Rachel Zegler
- Episode 30Kieran Culkin, Ta-Nehisi Coates
- Episode 31Seth Meyers, Mohanad Elshieky
- Episode 32Governor Tim Walz, John Oliver
- Episode 33John Dickerson, Lenny Kravitz
- Episode 34Paul Bettany, Mike Birbiglia
- Episode 35Javier Bardem, Curtis "50 Cent" Jackson
- Episode 36John Krasinski, Francis Ford Coppola
- Episode 37Zoe Saldaña, Ken Burns
- Episode 38Billy Bob Thornton, Sharon Horgan
- Episode 39Josh Brolin, Kacey Musgraves
- Episode 40President Bill Clinton, Kacey Musgraves
- Episode 41Paul Mescal, Elvis Costello & T Bone Burnett
- Episode 42House Democratic Leader Hakeem Jeffries, Jeffrey Wright
- Episode 43Daniel Craig, Auli'i Cravalho
- Episode 44Selena Gomez, Seth Meyers
- Episode 45Anderson Cooper, Andy Cohen, Doechii
- Episode 46Kate McKinnon, Peter Sarsgaard, Ben Folds
- Episode 47Billy Crystal, Arooj Aftab
- Episode 48Mindy Kaling, Saul Trujillo
- Episode 49Dua Lipa, Jon Batiste
- Episode 50Timothée Chalamet, Sabrina Carpenter
- Episode 51Nicole Kidman, Bill Skarsgård
- Episode 52Elton John, Brandi Carlile
- Episode 53Adrien Brody, Ben Schwartz
- Episode 54Edward Norton
- Episode 55Representative Adam Kinzinger
- Episode 56Tilda Swinton, Isabella Rossellini
- Episode 57Alan Cumming, Diane Morgan
- Episode 58Ben Stiller, June Squibb
- Episode 59Jeremy Bash, David Schwimmer, Kwame Alexander
- Episode 60Josh Gad, Betty Gilpin
- Episode 61Adam Scott, Secretary of the Treasury Janet Yellen
- Episode 62Kate Winslet, Jharrel Jerome
- Episode 63Jon Favreau, Jon Lovett, Tommy Vietor, Jalen Ngonda
- Episode 64Michelle Yeoh, Britt Lower
- Episode 65John Dickerson, Willow Avalon
- Episode 66Drew Brees, Morris Chestnut
- Episode 67Deion Sanders, Kane Brown
- Episode 68Chris Hayes, Nicole Scherzinger
- Episode 69Drew Barrymore, Brandon Scott Jones
- Episode 70Will Ferrell, FLO
- Episode 71Nicole Kidman, Jacob Soboroff
- Episode 72Lin-Manuel Miranda, Audra McDonald
- Episode 73Samantha Power, Miles Teller, W. Kamau Bell
- Episode 74Damon Wayans Jr., Daniel Boulud
- Episode 75Elton John, Melanie Lynskey, Leon Thomas
- Episode 76John Oliver, The War and Treaty
- Episode 77George Clooney, Alan Ritchson
- Episode 78Robert De Niro, Tamara Tunie
- Episode 79Al Roker, Monica Lewinsky
- Episode 80Woody Harrelson, Wendell Pierce
- Episode 81Drew Barrymore, Bong Joon Ho
- Episode 82Guy Fieri, Pamela Brown
- Episode 83RZA, Paul Mecurio, Father John Misty
- Episode 84Brian Tyree Henry, Tony Hawk
- Episode 85Pete Buttigieg
- Episode 86Jake Tapper, Paris Paloma
- Episode 87Sterling K. Brown, Reid Hoffman
- Episode 88Cate Blanchett, Tramell Tillman
- Episode 89Nathan Lane, Ezra Klein
- Episode 90Michael Fassbender, Uzo Aduba, the Voidz
- Episode 91Gary Oldman
- Episode 92Jake Gyllenhaal, Roxane Gay
- Episode 93Jenna Ortega, Erin Maguire, Megan Moroney
- Episode 94Seth Rogen, Carrie Coon
- Episode 95Senator Chuck Schumer, Michelle Buteau
- Episode 96Maurice DuBois, Jonathan Groff
- Episode 97Michelle Williams, Max Thieriot
- Episode 98Pierce Brosnan, Hannah Einbinder
- Episode 99Noah Wyle, Jenny Slate
- Episode 100Senator Cory Booker, Jalen Brunson
- Episode 101Woody Harrelson, Michael Lewis
- Episode 102Sheryl Lee Ralph, Paul W. Downs
- Episode 103Sarah Snook, Melinda French Gates
- Episode 104David Oyelowo, Finn Wolfhard, OK Go
- Episode 105Senator Elizabeth Warren
- Episode 106Senator Raphael Warnock, Joe Manganiello
- Episode 107Wanda Sykes, Cole Escola
- Episode 108Will Ferrell, Amber Ruffin
- Episode 109Jen Psaki, d4vd
- Episode 110Walton Goggins, John McWhorter
- Episode 111Jim Gaffigan, Suleika Jaouad
- Episode 112Rachel Maddow, Gillian Welch, David Rawlings
- Episode 113Christine Baranski, Stellan Skarsgård
- Episode 114Bill Gates, Paula Poundstone
- Episode 115Ryan Reynolds, Representative Jasmine Crockett
- Episode 116Father James Martin, Alexander Skarsgård, Professor Brian Cox
- Episode 117Nick Kroll, Emily Osment
- Episode 118Senator Bernie Sanders, Pavement
- Episode 119Angela Bassett, Bradley Whitford
- Episode 120James Comey, Meghann Fahy
- Episode 121Natalie Portman, Dawn Staley
- Episode 122Paul Giamatti
- Episode 123Jean Smart, Governor Josh Stein
- Episode 124Former New Zealand Prime Minister Jacinda Ardern
- Episode 125Mark Hamill, Cristin Milioti
- Episode 126Cynthia Erivo, Tony Gilroy
- Episode 127William Shatner & Neil deGrasse Tyson
- Episode 128Nicolle Wallace, Cyndi Lauper
- Episode 129Colman Domingo, The Cast of Slow Horses
- Episode 130John C. Reilly, Eva Victor
- Episode 131Mariska Hargitay, Senator Tammy Duckworth
- Episode 132Nate Bargatze, Kerry Condon
- Episode 133Allison Williams, Damson Idris, Model/Actriz
- Episode 134Paul Simon, Representative Maxwell Frost
- Episode 135Idris Elba, Brad Lander, Zohran Mamdani
- Episode 136John Cena, Lorde
- Episode 137Clarissa Ward, Michael C. Hall, Sienna Spiro
- Episode 138Stephen A. Smith, Liza Colón-Zayas
- Episode 139Joaquin Phoenix, Megan Stalter
- Episode 140Owen Wilson, Dr. Francis Collins
- Episode 141Senator Adam Schiffff, Anthony Carrigan, Noah Cyrus
- Episode 142Sandra Oh, Dave Franco
- Episode 143Bad Bunny, Leanne Morgan
- Episode 144Steve Buscemi, Molly Gordon
- Episode 145Governor Josh Shapiro, Alex G
- Episode 146Matt Rogers, Bowen Yang, Ocean Vuong
- Episode 147Jamie Lee Curtis, Rachael & Vilray
- Episode 148Liam Neeson, Senator Elissa Slotkin
- Episode 149Vice President Kamala Harris, Renée Rapp
- Episode 150Julia Garner, Former U.S. Labor Secretary Robert Reich
- Episode 151Fred Armisen, Governor JB Pritzker
- Episode 152Josh Brolin, The Black Keys
- Episode 153Senator Alex Padilla